Taiwan, a hotspot for malicious targets of cyber-attacks due to its role as a key link of high-tech in global supply chain. From national defense and security perspectives, it really needs more strategic thinking and proactive measures to counter cyber-threats - a non-stop, complex and global security issue. However, comparing the scale of Taiwan defense industrial suppliers with the extensive defense industrial base of the United States, it requires a collaborative effort of diverse stakeholders to collectively explore how to establish a constructive mechanism similar to the CMMC that aligns with national security needs and its own defense industrial environment. And, this will aim to establish a stronger cybersecurity resilience for its national defense supply chain. It is, therefore, urged and anticipated that Taiwan government set a much more aggressive mission goal with proactive cross-department integration and support efforts to promote much closer cooperations between US-Taiwan defense industry and help industry engaging the CMMC and compliance to the NIST related standards.